产品货号:
Z28604
中文名称:
TNPO3抗体
英文名称:
Anti-TNPO3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TNPO3 Antibody |
指标别名 | TNPO 3;Imp12;Importin 12;IPO12;MTR10A;TNPO3;Transportin 3;Transportin SR;TRN-SR2;TRNSR |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB |
基因名称 | TNPO3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TNPO3 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human TNPO3.The immunogen is located within amino acids 140 - 190 of TNPO3. |
计算分子量 | 104kDa |
成分 | TNPO3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TNPO3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins,binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins.Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated.More recently,TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration,suggesting that TNPO3 may be an important drug target in HIV treatment.At least three isoforms of TNPO3 are known to exist. |
Uniprot ID | Q9Y5L0 |
基因名全称 | Transportin 3 |
蛋白名全称 | Transportin 3 |
推荐稀释比 | TNPO3 antibody can be used for detection of TNPO3 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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